Cell Solutions
​Product Details
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Isolated from healthy human donors
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Amenable to both 2D and 3D culture systems
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Post-thaw viability > 80%
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Characterization
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Expression of CD31, CD146, and vWF​
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Do not express TE7 and GFAP
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NAS score between 0-1 (confirmed by board certified pathologist​)
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The Mosaic Cell Sciences Advantage
Mosaic Cell Sciences' repository of primary healthy and diseased Human Liver Endothelial Cells serves as an invaluable resource for scientists, unlocking new frontiers in the identification and development of translational therapeutic interventions. Human liver endothelial cells play a crucial role in maintaining liver homeostasis by actively participating in the regulation of blood flow, nutrient exchange, and immune responses within the liver microenvironment. Using our meticulously curated solutions, researchers gain access to a comprehensive platform that allows them to delve into the intricate mechanisms underlying liver function.
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In the context of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and its advanced stage, Metabolic Dyfsunction-Associated Steatohepatitis (MASH), our diseased liver endothelial cells offer a unique opportunity to investigate the initiation and progression of these pathologies. These cells possess the remarkable capability to induce a diseased phenotype during the initial stages of MASH/MASLD mimicking the complex cellular changes observed in vivo. By utilizing our Cell Solutions scientists gain critical insights into the molecular and cellular events that contribute to disease onset. Learn more about our nonparenchymal cell offerings by downloading the brochure below.