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Healthy Hepatic Stellate Cells

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Human Hepatic Stellate Cells
(from healthy donors)

Item Number: 121903-03
Cell Density: 1 million cells/vial

Product Information: Hepatic Stellate Cells

hepatic stellate cells from donor HL230012

  • Amenable to both 2D and 3D culture systems 

  • Post-thaw viability > 80%

  • Characterization

    • Expression of GFAP and αSMA

    • Do not express TE7 and CD31

  • NAS score between 0-1 (confirmed by board certified pathologist​)

Additional information

Mosaic Cell Sciences' Healthy and Diseased Human Stellate Cells offer scientists the ability to capture and assess the pathogenesis and/or the role of fibrogenesis in NASH/NAFLD. The resident cell within the Space of Disse, Stellate Cells store 80% of the body's vitamin A reserves within their cytoplasm. During NASH/NAFLD, activation of Stellate Cells from a quiescent state, due to inflammatory signaling, induces extracellular matrix deposition and fibrosis. Primary Human Stellate Cells can be utilized to discover the complex interplay between liver parenchymal and non-parenchymal cells in both healthy and disease conditions. Learn more about our nonparenchymal cell offerings by downloading the brochure below.

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