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Cell Solutions
Human Kupffer Cells -
MASH/MASLD Donors
Product Number | Cells Per Vial | Price |
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121103-03 | 1 x 10^6 Cells/Vial | $1,400 |
New Customers Receive 25% Off Their First Order
​Product Details
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Amenable to both 2D and 3D culture systems
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Post-thaw viability > 80%
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Characterization
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Expression of CD11b and CD163
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Do not express TE7
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Inducible cytokine production by LPS
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NAS score between 0-3 (confirmed by board certified pathologist​)
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​Steatosis qualified as > 30% macrovesicular, microvesicular, or a combination of the two.
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Download our primary human non-parenchymal cell brochure
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The Mosaic Cell Sciences Advantage
Mosaic Cell Sciences' Healthy and Diseased Kupffer Cells (KCs) provide an opportunity to study the diverse functions of liver-resident macrophages beyond their role in innate immunity against gastrointestinal xenobiotics. These phagocytic cells detect pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) from foreign substances and damaged cells, help clear excessive gut microbiota, remove spent erythrocytes, and recruit neutrophils to the liver sinusoid during inflammation. Our MASH/MASLD KCs enable researchers to investigate the complex biological mechanisms of the hepatic system in pathological models, supporting toxicity assessments and drug discovery efforts. Download our brochure to learn more about our nonparenchymal cell offerings.
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