MASH/MASLD Liver Endothelial Cells
Liver Endothelial Cells
(from NASH/NAFLD donors)
Item Number: 120503-03
Cell Density: 1 million cells/vial
Product Information: MASH/MASLD Liver Endothelial Cells
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Amenable to both 2D and 3D culture systems
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Post-thaw viability > 80%
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Characterization
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Expression of CD31, CD146, and vWF​
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Do not express TE7 and GFAP
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NAS score between 0-3 (confirmed by board certified pathologist​)
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Steatosis qualified as > 30% macrovesicular, microvesicular, or a combination of the two.​​
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Additional information
​Mosaic Cell Sciences offers our Primary Human MASH/MASLD Human Liver Endothelial Cells for scientists to drive discovery in the etiopathology of MASH/MASLD. Using our meticulously curated nonparenchymal cells, researchers gain access to a comprehensive platform that allows them to delve into the intricate mechanisms underlying liver function. In the context of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and its advanced stage, Metabolic Dysfunction-Associated Steatohepatitis (MASH), our diseased liver endothelial cells offer a unique opportunity to investigate the initiation and progression of these conditions. These cells possess the remarkable capability to induce a pathogenic phenotype during the initial stages of NASH/NAFLD, mimicking the complex cellular changes observed in vivo. By studying the behavior of these cells, scientists can gain critical insights into the molecular and cellular events that contribute to disease onset to advance therapeutic interventions to impact the quality of life of those impacted by NASH/NAFLD. Learn more about our nonparenchymal cell offerings by downloading the brochure below.