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Cell Solutions
Hepatic Stellate Cells -
MASH/MASLD Donors
Product Number | Cells Per Vial | Price |
|---|---|---|
121903-03 | 1 x 10^6 Cells/Vial | $1,600 |
New Customers Receive 25% Off Their First Order
​Product Details
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Isolated from MASH/MASLD Human Donors
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Amenable to both 2D and 3D culture systems
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Post-thaw viability > 80%
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Characterization
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Expression of GFAP and αSMA
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Do not express TE7 and CD31
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NAS score between 0-3 (confirmed by board certified pathologist​)
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​Steatosis qualified as > 30% macrovesicular, microvesicular, or a combination of the two
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Download our non-parenchymal cell brochure to learn more
The Mosaic Cell Sciences Advantage
Our Primary Human MASH/MASLD Hepatic Stellate Cells (HSCs) empower researchers to explore the role of nonparenchymal cells in the progression of MASH/MASLD and identify therapeutic targets in non-alcoholic liver disease. In MASH/MASLD, the activation of stellate cells causes extracellular matrix protein buildup in the Space of Disse, obstructing the transport of nutrients, drugs, and waste from the liver sinusoid to hepatocytes. The complex interactions between stellate cells, hepatocytes, innate immune cells, and liver sinusoidal endothelial cells create a feedback loop that fuels inflammation. This progression is driven by the pro-inflammatory factors secreted by MASH/MASLD HSCs. Discover how Mosaic Cell Sciences' Primary MASH/MASLD HSCs can enhance your drug discovery research. Download our brochure to learn more about our nonparenchymal cell offerings.
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